Moore has been under pressure for weeks, with the Bulldogs losing seven of their last nine games.
Assistant coach Jim Dymock will take charge of the side for tomorrow night’s clash and the remainder of the season.
Moore has received support from Bulldogs chief executive Todd Greenberg and board members in recent weeks, but has decided to fall on his sword after being toldhe was being axed at the end of the season.
New South Wales Origin coach Ricky Stuart has been linked with the club.
Moore released a statement which read: “On Tuesday 12 July, I was told by Ray Dib, Canterbury-Bankstown RLFC Chairman, and Todd Greenberg, club CEO, that my services as head coach were no longer required by the club after season 2011.
“Having considered the impact this will have on my family, my support staff and the players, and importantly, the club that I love and have been involved with since the early 1970’s, I will stand down effective immediately having helped the team complete its preparation for Friday night’s game against the Warriors in Auckland.”
“I feel very privileged to have been a part of a great club for so long and I want to thank all who have been a part of this journey with me.”